Horse chestnut seed יִשְׂרָאֵל

It is a tall tree of the seven leaf tree genus in the Sapindaceae family, native to southeastern Europe, Greece, and West Asia, and later naturalized and cultivated in many parts of the world such as North America.

The seeds of medicinal plants in the seven leaf tree genus have the effects of regulating qi, broadening the middle, and relieving stomach pain. They contain triterpenoid saponins, sugars, coumarins, flavonoids, and other components. The main active substance saponins have good anti-inflammatory, anti edema, anti oxygen free radical, and gastrointestinal function regulating effects

1. Anti inflammatory and anti edema effects

Aescin (esculin) has the effects of strengthening blood vessels, reducing vascular permeability, reducing swelling, and anti-inflammatory.

Sodium Aescinate is a non permeable dehydrating agent. Compared with traditional dehydrating agents such as mannitol and hormones, it has a longer action time and no "rebound" phenomenon. It will not cause water and electrolyte disturbances or nephrotoxic effects caused by long-term use

2. Anti oxidative free radical effect

Oxygen free radicals have strong oxidizing properties and have an oxidizing effect on intracellular substances, especially unsaturated fatty acids. The human brain contains a large amount of unsaturated fatty acids, which are extremely sensitive to oxidative damage. Research has shown that the excessive production of oxygen free radicals leads to damage after cerebral ischemia-reperfusion, and sodium saponin from seven leaves has the effect of improving nerve cell damage caused by oxygen free radicals.

3. antitumor activity

Aescin has a certain inhibitory effect on the proliferation of acute and chronic myeloid leukemia cells HL-60 and K562, and can exert significant effects by inducing cell apoptosis.

4. Venous and vascular regulatory effects

Seven leaf saponin sodium has a very good improvement effect on varicose veins, venous thrombosis, chronic lower limbs, venous insufficiency, and lower limb arterial obstructive diseases. It can significantly improve edema symptoms and has good tolerance.

5. Gastrointestinal function regulation

Seven leaf saponin sodium has a certain regulatory effect on the digestive system, with anti secretion and inhibitory effects on gastric emptying. The inhibitory effect on gastric acid secretion is of great significance in the prevention and treatment of gastric ulcers.

Unsuitable population

Pregnant and breastfeeding women with unclear safety information are not recommended for use